Technology - Soft Ionization by Chemical Reaction in Transfer (SICRIT®)

The SICRIT® ionization source is interfaced with the atmospheric pressure inlet of a mass spectrometer (MS) which is constantly drawing air through the source.
By igniting a cold plasma inside the source, every substance drawn in is passing the plasma and ionized on its way into the MS. In comparison with current systems this patent pending design decouples the ionization from the sample delivery. Therefore, tidious sample pretreatment and lengthy adjustment/optimization of the ionization position and parameters are obsolete.

Spray or Plasma Jet

MS Inlet

MS Inlet

Analyte Molecules
Reagent Ions
Analyte Ions

SICRIT® Source

Conventional Ionization

SICRIT® Ionization

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SICRIT® Technology
Flyer
Download the
SICRIT®
Technical Note

SiCRIT® Analysis Example: Coffee

Vanillin + H+
(153.05 amu)

SICRIT Analysis Example: Coffee

1 single coffee Bean

Caffeine + H+ (195.09 amu)

1 second
measurement

Details: Data were recorded on an LTQ Orbitrap system by placing 1 coffee bean in front of the SICRIT® source in a heated (80°C) gas stream.

More than 100 Aroma compounds can be identified!

technological advantages

Scientific ​Clients

Industrial ​Clients

​Mass spectrometry has never been as simple as with SICRIT®  
SICRIT® can transform each mass spectrometer into an electronic nose

STATUS QUO:

Existing screening methods based on ambient-MS  are still very expensive and are stand alone methods. SICRIT® can be easily implemented in existing routine (ESI / APCI) analysis methods and can also be combined with HPLC and GC for improved quantification.

In-line process control measurements by mass spectrometry were not possible due to high instrumental and human effort in sample preparation. Yet, there was no other real-time measurement of volatile substances and emissions available.

SICRIT®
​PROVIDES:

  • ​ONLINE MS PROCESS ​CONTROL
  • ROBUST OPERATION (24/7)
  • ​NO TRAINED PERSONAL NEEDED
  • ​AUTOMATED ​QUALITY ​CONTROL
  • ​ANALYSIS IN ​LESS THAN 1 SECOND
  • SUPERIOR LEVEL OF ANALYTICAL INFORMATION
  • ​TRAINABLE AUTOMATED ​DECISION MAKING / SORTING
  • LOW COST PER ANALYSIS
  • INDUSTRY 4.0 COMPATIBLE

  • HIGHER ​SENSITIVITY (SUB PPT)
  • UPGRADE TO OLD INSTRUMENTS
  • ​DIRECT SCREENING AND QUANTIFICATION
  • COMBINATION WITH ​GC, ​HPLC AND ​SPME
  • CAN BE USED ​IN SERIES WITH ​ESI OR ​APCI
  • ROBUST OPERATION (24/7)
  • IONIZES MORE ANALYTES
    ​(e.g. PERFLUORINATED ALKANES)
  • VERY ​SOFT IONIZATION
    ​(COMPARABLE TO ESI)
  • NO NOBLE GAS CONSUMPTION
  • ​LOW PURCHASE AND MAINTENANCE ​COST