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App
Notes
#Breath
SICRIT®-HRMS for Metabolic Profiling through Direct Breath Analysis
We demonstrate an easy extension of conventional capabilities for the SICRIT® ionization source, coupled to a high-resolution MS instrument, through a metabolomic-based breath analysis and how groups of target masses can be isolated and analyzed for potential biomarker identification.
#Pesticides
Performance Evaluation of 41 Common Pesticides by LC-SICRIT featuring Shimadzu LC-40 and 9030 LC-MS QToF
To bridge this gap between the different pesticide analyte classes, and provide a new perspective on LC ionization, we present SICRIT® LC-Module. In this study, we utilize a HRMS coupled to the SICRIT® LC-Module to analyze 41 common pesticides.
#Nitrosamines
Comparison of SICRIT® and APCI in the Analysis of Nitrosamines with Liquid Chromatography
In this study we provide a direct comparison of APCI and the SICRIT® ionization source for the analysis of 7 Nitrosamines by LC-HRMS.
#Lipids
LC-SICRIT®-HRMS Analysis of Non-Polar Lipids featuring Shimadzu Nexera LC and 9030 LC-MS QToF
In this set of measurements, we demonstrate the detection capabilities of 8 different Triacyl-glycerides of varying length and saturation with LC-SICRIT®-HRMS.
#Breath
SICRIT®-HRMS for Targeted Exposomic-Metabolomic Research through Direct Respiratory Analysis
We demonstrate an extension of conventional capabilities for the SICRIT® ionization source, coupled to a high-resolution MS instrument, through a metabolomic-based breath analysis and how efficient it is to conduct targeted studies of dynamic metabolomic profiles, of the lungs, for an individual person, in realtime.
#Aroma #Flavor #Food
Characterization of cherry-type flavorings based on volatile compounds by means of the HaVoc sensory system
Flavorings are very popular as they provide an extra taste to foods and beverages such as pastries, ice cream, sweets, coffee, or tea.
#Nitrosamines
GC-SICRIT®-MS: Fast and sensitive analysis of 6 nitrosamines by replacing helium with hydrogen as carrier gas
A fast determination of 6 nitrosamine compounds by GC-SICRIT®-(LC)MS is demonstrated.
#Nitrosamines
Ultra-Sensitive GC-SICRIT®-HRMS Analysis of Nitrosamines in Pharmaceutical Samples featuring Hydrogen as GC Carrier Gas and Shimadzu LCMS-9030 QToF
In this study we demonstrate ultra-sensitive determination of various nitrosamine compounds by GC-SICRIT®-MS using H2 as carrier gas and full scan high resolution MS data from Shimadzu LCMS-9030.
#Nitrosamines #Shimadzu
Coupling of GC and LCMS Systems via SICRIT® Soft Ionization Source for Sensitive Detection of Nitrosamines
Nitrosamine have emerged as impurities of mature concern in pharmaceutical preparations. Initially detected by the US FDA in drugs used in the treatment of hypertension and heart failure containing Sartan as active pharmaceutical ingredients.
#Nitrosamines
Sensitive Detection of Nitrosamines for Drug Quality Control using SICRIT® Soft Ionization-MS
In this study we demonstrate sensitive determination of nitrosamine compounds by GC-soft ionization-MS outperforming GC-MS and LC-MS methods in view of drug quality control.
#Breath
SICRIT® – HRMS for Exhaled Breath Analysis
We show, how easily the SICRIT® Ion source can be adapted to high-resolution MS instruments for trace analysis of biomarkes and metabolites in exhaled breath.
#SPME Analyses
SICRIT® Technology for Fast and Direct SPME-MS Analysis of Environmental Trace Contaminants
We present a versatile method for direct and quantitative identification of trace contaminants in environmental samples without sample preparation using SICRIT® soft
ionization technology.
#CWA
Chemical Warfare Agents – Direct SICRIT®-MS Analysis
Although chemical warfare agents (CWA) and their use are outlawed, they still are an imminent threat to people all over the world.
#Explosives
Fast and Direct Detection of Explosives using SICRIT®-MS
The detection of explosives and explosive-related compounds is a high-priority tasks in recent years for homeland security and counter-terrorism applications.
#PFCA
Fast and Direct Detection of Perfluorocarboxlyic acids (PFCA) with SICRIT®-MS
Per- and polyfluoroalkyl compounds (PFAS), especially their carboxylic acids (PFCA), are ubiquitously used chemicals as flame retardants, surfactants, and coatings.
#Alkanes
Soft ionization GC-HRMS of n‑Alkanes C8 – C20 (SCIEX TripleTOF® 5600)
We introduce a versatile new method for trace analysis of non-polar short-chain n‑alkanes C8-C20 using GC-SICRIT®-HRMS.
#Alkanes
Soft ionization GC-HRMS of n‑Alkanes C8 – C20 (Thermo LTQ Orbitrap XL)
We introduce a versatile new method for trace analysis of non-polar short-chain n‑alkanes C 8 ‑C 20 using GC-SICRIT® ‑HRMS.
#Alkylamine
GC soft ionization coupling to LC-MS with SICRIT® (Thermo LTQ Orbitrap XL)
Due to historic reasons the world of mass spectrometry is still divided into GC-MS and LC-MS systems and users thereof.
#Coffee
Coffee Aroma Profiling – Direct SICRIT® HR-MS Analysis
Coffee is one of the most popular beverages and known for its manifold aroma profiles.
Product
Notes
#SC-30
SICRIT® Ionization Set SC-30
The SICRIT® (Soft Ionization by Chemical Reaction In Transfer) SC-30 Ionization Set is a plug & play flowthrough ionization add-on for mass spectrometers with an atmospheric pressure inlet. It can be interfaced with almost all LC-MS systems on the market.
#GC-SPME
SICRIT® GC/SPME Module
The SICRIT® GC/SPME Module connects state-of-the-art sample enrichment and separation techniques with your SICRIT® Ion Source.
#Sampling-Line
SICRIT® Heated Sampling Line
The SICRIT® Heated Sampling Line is designed to improve the collection and transport of analytes to the MS and allows for countless new ways to bring samples to the MS instrument.
#LC-SFC-Module
SICRIT® LC/SFC Module
The SICRIT® LC/SFC Module enables the connection from conventional liquid or supercritical fluid chromatography to mass spectrometers using the SICRIT® ionization source.
Webinars
07.03.2024 SICRIT UNIVERSE Event 2024
Our experiences developing SICRIT methods for direct analysis
Prof. Dr. Nicole Strittmatter (TU Munich)
07.03.2024 SICRIT UNIVERSE Event 2024
Development of a very fast method for authentication analysis of food exploiting molecular fingerprints using a direct injection approach via SICRIT-q-TOF-MS and subsequent multivariate data analysis
Dr. Andreas Schmidberger (Labor Friedle)
07.03.2024 SICRIT UNIVERSE Event 2024
SICRIT for Enhanced Quality Control of Phytopharmaceuticals and Essential Oils: Method Development and Applications
Dr. Christian Steuer (ETH Zürich)
07.03.2024 SICRIT UNIVERSE Event 2024
Interfacing LC-ESI and GC-DBDI to the same instrument a versatile setup for a MS Core Facility
Dr. Natalia Gasilova (EPFL Lausanne)
19.02.2024
Rapid analysis of illicit drugs and chemical profiling of fingerprints
Dr. Jan Bucek (Plasmion)
23.11.2021
SICRIT-MS for in-situ analysis of VOCs in various samples -
Prof. Zhou Jiang (Peking University)
23.11.2021
HELIOS/SICRIT/mass spectrometry for analysis of aerosols in engine exhaust -
Prof. Christoph Haisch ( TU Munich)
23.11.2021
Beyond standard analytical workflows – Coupling of GC and Shimadzu LCMS instruments with Plasmion SICRIT® ion source -
Dr. Sascha Rexroth (Shimadzu)
23.11.2021
Experiences with the Plasmion SICRIT Flow-through Dielectric Barrier Discharge Ion Source -
Robert (Chip) Cody, Ph.D. (JEOL)
23.11.2021
Real-time monitoring of cereal roasting processes by ultra-highresolution mass spectrometry with plasmion ionization -
Leopold Weidner (HHZ Munich)
05.05.2020
GC Coupling to LC-MS Instruments ‑Expand your Mass Spectrometric “View” with SICRIT -
Dr. Jan-Christoph Wolf (Plasmion)
04.05.2020
Direct MS Screening – Get Results Faster with SICRIT -
Dr. Jan-Christoph Wolf (Plasmion)