Soft Ionization by Chemical Reaction In Transfer

# Mass Spectrometry

Mass spectrometry is one of the most powerful techniques in chemical analysis. Mass spectrometers enable to detect and characterize substances based on the mass-to-charge ratio of their molecules. To do so, MS comprise two basic components: an ionization source and a mass analyzer.

Mass Spectrometry

Ionization Source:

Mass spectrometers are only capable to measure charged molecules (ions). Thus, the ionization source generates ions by ionizing molecules.

Mass Analyzer:

The mass analyzer measures the mass of ionized molecules or rather the mass-to-charge ratio of ions.

Ionization Source

# Ionization Source

With conventional atmospheric pressure methods, the ions are mostly formed outside the inlet of a MS. This implies that the substance to be analyzed (e.g. coffee) cannot be analyzed directly, but is usually "sprayed" into the MS in the form of a sample (liquid extract) via the ionization source.

Conventional
Ionization Technologies

Analyte Molecules

Reagent Ions

Analyte Ions

MS Inlet

Ionization Source

vs.

MS Inlet

Ionization Source

The patented SICRIT ionization source extends the atmospheric pressure inlet of the MS and ionizes all molecules which are drawn into the MS by its inherent vacuum. Due to the flow-through design of the ionization source, it is dedicated for online-monitoring of volatiles without any consumables as well as for demanding hyphenation techniques.

ADVANTAGES

SICRIT
Ionization Technology